Deborah Pinson Hyink
Box 1243
Mt. Sinai School of Medicine
1 Gustave L. Levy Place, Rm 23-29
New York, NY 10029-6574
phone: (212) 241-9431
fax: (212) 987-0389
Email: deborah.hyink@mssm.edu
ACADEMIC
APPOINTMENTS:
2003-
Assistant Professor, Mount Sinai School of Medicine
2001-2003
Instructor, Mount Sinai School of Medicine
EDUCATION:
1985
B.S. (Biology) Furman University, Greenville, SC
1990
M.S. (Biological Sciences) Clemson University, Clemson, SC
Thesis
title: The metanephridial system of Themiste alutacea
(Sipuncula)
1995
Ph.D. (Cell Biology) University of Alabama at Birmingham,
Birmingham,
AL.
Dissertation
title: Vascularization of the Developing Kidney
2001-2002
Database application and development (Certificate program)
Columbia
University, New York, NY
POSTDOCTORAL
TRAINING:
1995-
1996 Postdoctoral Fellow, Johns Hopkins School of Medicine, Division of
Nephrology
1996-
2000 Associate, Mount Sinai School of Medicine, Division of Renal Medicine
PUBLICATIONS:
1. Hyink
DP and Abrahamson DR: Origin of the glomerular vasculature in the developing
kidney.
Seminars
Nephrol 15:300-314, 1995
2.
Hyink DP, Tucker DC, St.John PL, Leardkamolkarn V, Accaviti MA, Abrass CK, and
Abrahamson
DR: Endogenous origin of glomerular endothelial and mesangial cells in grafts
of embryonic
kidneys.
Am J Physiol 270:F886-F899, 1996
3.
Robert B, St.John PL, Hyink DP, and Abrahamson DR: Evidence that embryonic
kidney cells
expressing
flk-1 are intrinsic, vasculogenic angioblasts. Am J Physiol 271:F744-F753, 1996
4.
Abrahamson DR, Robert B, Hyink DP, St. John PL, and Daniel TO: Origins and
formation of
microvasculature
in the developing kidney, Kidney Int, 54:S67:S7-S11, 1998
5.
Hosono, S, Luo X, Hyink DP, Schnapp LM, Wilson PD, Burrow CR, Reddy JC, Atweh
GF, and
Licht
JD: WT1 expression induces features of renal epithelial differentiation in
mesenchymal 3T3
fibroblasts,
Oncogene, 18:417-427, 1999
6.
Hyink DP, Rappoport JZ, Wilson PD, and Abramson RG: Expression of the urate
transporter/channel
is developmentally regulated in human kidneys. Am J Physiol 281: F875-886, 2001
7. Li
X, Li H-P, Amsler K, Hyink D, Wilson PD, Burrow CR: PRKX, a phylogenetically
and
functionally
distinct cAMP-dependent protein kinase, activates renal epithelial cell
migration and
morphogenesis.
PNAS 99(14):9260-9265, 2002
8.
Kaletta T, Bogaert T, Van der Craen M, Van Geel A, Dewulf N, Buechener M,
Barstedt R, Hyink
D, Li
H, Geng L, Burrow CR, Wilson PD: Towards understanding the polycystins. Nephron
93:E9-
E17,
2003
9.
Gross I, Morrison DJ, Hyink DP, Georgas K, English MA, Mericskay M, Hosono S,
Sassoon D,
Wilson
PD, Little M, Licht JD. The receptor tyrosine kinase regulator Sprouty1 is a
target of the tumor
suppressor
WT1 and important for kidney development. J Biol Chem. 278:41420-30, 2003
10.
Qiu L, Hyink DP, Gans WH, Amsler K, Wilson PD, Burrow CR: Midkine promotes
selective
expansion of the nephrogenic mesenchyme during kidney organogenesis. In Press